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代表性科研成果 
--南方医科大学皮肤病医院(广东省皮肤病医院) 发布时间:2023/6/25    【访问量:5924】 --
 

代表性科研成果:

1.        Deng, C.C. #, Hu, Y.F. #, Zhu, D.H. #, Cheng, Q., Gu, J.J., Feng, Q.L., Zhang, L.X., Xu, Y.P., Wang, D., Rong, Z.*, Yang, B.* Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases. Nat Commun. 2021 Jun 17;12(1):3709.

2.        Chen W#, Luo H#, Zeng L, Pan Y, Parr JB, Jiang Y, Cunningham CH, Hawley KL, Radolf JD, Ke W, Ou J, Yang J, Yang B*, Zheng H*. A suite of PCR-LwCas13a assays for detection and genotyping of Treponema pallidum in clinical samples. Nat Commun. 2022 Aug 9;13(1):4671.

3.       Xu, Y.*#, J. Zhang*, Y. Hu*, X. Li*, L. Sun, Y. Peng, Y. Sun, B. Liu, Z. Bian#, and Z. Rong#. 2021. Single-cell transcriptome analysis reveals the dynamics of human immune cells during early fetal skin development. Cell Rep 366: 109524.

4.       Lu P#, Zhao Y#, Xie Z#, Zhou H, Dong X, Wu GF, Kim BS, Feng J, Hu H. MrgprA3-expressing pruriceptors drive pruritogen-induced alloknesis through mechanosensitive Piezo2 channel. Cell Rep, 2023 ;42(4):112283.

5.       Deng CC#, Zhang LX#, Xu XY#, Zhu DH, Cheng Q, Ma SF, Rong ZL*, Yang B*. Risk SNP-mediated enhancer-promoter interaction drives keloid through lncRNA DEIK. British Journal of Dermatology, 2023, 23;188(1):84-93.

6.       Liu, J.#, Chen, J.#, Zhong, Y., Yu, X., Lu, P., Feng, J., Zhang, X., Ma, S., Yang, C., Yang, B.*, Rong, Z.* OSMRβ mutants enhance basal keratinocyte differentiation via inactivation of the STAT5/KLF7 axis in PLCA patients. Protein Cell. 2021 Aug;12(8):653-661.

7.       Deng CC#, Zhu DH#, Chen YJ, Huang TY, Peng Y, Liu SY, Lu P, Xue YH, Xu YP, Yang B*, Rong ZL*. TRAF4 promotes fibroblast proliferation in keloids by destabilizing p53 via interacting with the deubiquitinase USP10. Journal of Investigative Dermatology, 2019, 139(9): 1925-1935.

8.       Zhang, J.*, Y. Peng, Y. Hu, H. Guo, Y. Sun, X. Zhang, Q. S. Mi, and Y. Xu#. 2023. TFAM Deficiency‒Mediated Mitochondrial Disorder Affects Langerhans Cell Maintenance and Function. J Invest Dermatol 143: 508-513 e502.

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广东省卫健委 南方医科大学 南方医科大学本科招生信息网 南方医科大学研究生招生信息网

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